ADHD trials enroll children, adolescents, or adults depending on the protocol. Stimulant history, rating-scale scores, and school or work measures often appear. Pediatric studies have extra consent rules. We do not diagnose ADHD or recommend a stimulant. Sourced from ClinicalTrials.gov. Not a recommendation to join any study.
RecruitingNot a traditional drug phaseBoston, Massachusetts
National Pregnancy Registry for Psychiatric MedicationsThe National Pregnancy Registry for Psychiatric Medications is dedicated to evaluating the safety of psychiatric medications such as antidepressants, ADHD medications, sedative hypnotics, and atypical antipsychotics that many people take during pregnancy to treat a wide range of mood, anxiety, executive function, or psychiatric disorders. The goal of this Registry is to gather information on the safety of these medications during pregnancy, as current data is limited.
NCT01246765 · Official ClinicalTrials.gov record · Massachusetts General Hospital
RecruitingNot a traditional drug phaseSacramento, California
Not a traditional drug phase: VR Treatment for ADHDProblems with distraction are widespread in the 21st century, but for people with developmental delays or behavioral challenges they can have more damaging effects. For example, susceptibility to distraction is associated with worse school and social performance, lower high school graduation rates, and increased incidence of serious accidents.
NCT03221244 · Official ClinicalTrials.gov record · University of California, Davis
RecruitingNot a traditional drug phasePhoenix, Arizona
Not a traditional drug phase: testing The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care: for Coronavirus Infection (COVID-19)The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to measure the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
NCT04278404 · Official ClinicalTrials.gov record · Duke University
RecruitingPhase 4Baltimore, Maryland
Phase 4: testing Methylphenidate for Attention Deficit Hyperactivity Disorder CombinedAttention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurobehavioral disorder in childhood. Children with ADHD struggle in school due to problems with attention and high levels of impulsivity and hyperactivity.
NCT04421248 · Official ClinicalTrials.gov record · Donald Gilbert, MD, MS, FAAN, FAAP
RecruitingNot a traditional drug phaseBethesda, Maryland
Developing Brain, Impulsivity and CompulsivityBackground: Impulsivity is acting 'without thinking.' Compulsivity is being overly inflexible. People vary in how impulsive or compulsive they are.
NCT04631042 · Official ClinicalTrials.gov record · National Institute of Mental Health (NIMH)
RecruitingPhase 4Saraland, Alabama
Phase 4: testing 100mg SPN-812 for Attention-Deficit/Hyperactivity DisorderThis study will measure the how well it works and safety of SPN-812 (viloxazine extended release) in children 4 to 5 years of age with ADHD.
NCT04781140 · Official ClinicalTrials.gov record · Supernus Pharmaceuticals, Inc.
RecruitingNot a traditional drug phaseHershey, Pennsylvania
Not a traditional drug phase: Behavioral Parenting Intervention for ADHDAim: To examine if parental emotion regulation (ER) moderates the response to parent training interventions. H1: Reduced parental ER capacity will predict diminished how well it works for behavioral parent training to improve negative parenting behavior (NPB) and behavior problems in offspring with ADHD.
NCT05299814 · Official ClinicalTrials.gov record · Milton S. Hershey Medical Center
RecruitingPhase 1 / Phase 2Bethesda, Maryland
Phase 1 / Phase 2: Non-adaptive Floreo VR control for Attention Deficit Hyperactivity DisorderBackground: Children with attention deficit hyperactivity disorder (ADHD) often have cognitive problems. It may be hard for them to control their behaviors, concentrate for long periods, or make decisions.
NCT05608434 · Official ClinicalTrials.gov record · National Institute of Mental Health (NIMH)
RecruitingPhase 4Irvine, California
Phase 4: testing Randomization to either Amphetamine (AMP) class of stimulant medication or Methylphenidate (MPH) class of stimulant medication for ADHDThis study is a pragmatic clinical trial examining the comparative effectiveness of two stimulant medications (methylphenidate and amphetamine) in the treatment of ADHD in children and adolescents with autism. Using a sequential, multiple assignment randomization trial (SMART) design the study will not only assess these two medications but also the role of an increasingly popular class of ADHD medication, the alpha-2 agonists.
NCT05916339 · Official ClinicalTrials.gov record · Daniel Coury
RecruitingNot a traditional drug phaseOulu
Not a traditional drug phase: Parental Guidance for Attention Deficit Hyperactivity DisorderAttention deficit hyperactivity disorder (ADHD) is caused by an abnormality in the development of the central nervous system. Children with attention and executive function difficulties often need long-lasting rehabilitation and there is an increasing need for timely, cost-effective, and feasible rehabilitation interventions, where the training is targeted to support everyday life functional capacity.
NCT06123741 · Official ClinicalTrials.gov record · Merja Nikula
RecruitingNot a traditional drug phaseCalgary, Alberta
Pharmacogenomics of Stimulant Treatment ResponseThe "Pharmacogenomics of Stimulant Treatment Response" (PGx-STaR) study aims to identify genetic profiles related to methylphenidate treatment outcomes in children and adolescents aged 6-24 with Attention deficit/hyperactivity disorder (ADHD).
NCT06221358 · Official ClinicalTrials.gov record · University of Calgary
RecruitingNot a traditional drug phaseParis
Not a traditional drug phase: Sulforaphane for Attention Deficit DisorderIt is the most common neurodevelopmental disorder in children and adolescents. Its prevalence is estimated at 5.9% in this population.
NCT06594536 · Official ClinicalTrials.gov record · Assistance Publique - Hôpitaux de Paris
RecruitingNot a traditional drug phaseLos Angeles, California
Not a traditional drug phase: Trigeminal Nerve Stimulation (TNS) for Fetal Alcohol Spectrum DisordersThis is an open-label trial of trigeminal nerve stimulation (TNS) for children aged 8-12 years with attention deficit hyperactivity disorder (ADHD) putatively due to prenatal alcohol exposure (PAE). TNS has been successful in treating pediatric ADHD generally and it is US Food and Drug Administration (FDA)-cleared for this condition.
NCT06847165 · Official ClinicalTrials.gov record · University of California, Los Angeles
RecruitingNot a traditional drug phaseBeijing, Chaoyang District
Not a traditional drug phase: testing Chinese herbal medicine for AcupunctureThis study aims to measure the how well it works of acupuncture as a treatment for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 6-12 years. Using a mixed-methods approach, the research will triangulate data from acupoint data mining, treatment outcomes assessment, and patient perspectives to provide a comprehensive analysis of acupuncture's potential therapeutic benefits for ADHD.
NCT06860763 · Official ClinicalTrials.gov record · The Third Affiliated Hospital of Beijing University of Chinese Medicine
RecruitingPhase 3Tokyo
Phase 3: testing EB-1020 (Centanafadine) 164.4 mg for Attention Deficit Hyperactivity Disorder (ADHD)This study wants to measure the safety of long-term administration of mainly high doses of EB-1020 over 52 weeks in patients who have completed the neither you nor the study doctors know who gets the real treatment trial (405-102-00112) conducted in Japan
NCT06926829 · Official ClinicalTrials.gov record · Otsuka Pharmaceutical Co., Ltd.
RecruitingPhase 2 / Phase 3Tokyo
Phase 2 / Phase 3: testing EB-1020 (Centanafadine) 164.4 mg for Attention Deficit Hyperactivity Disorder (ADHD)This study wants to measure the how well it works and examine the safety of two doses of EB-1020 QD XR capsule administered once daily orally in adult ADHD patients.
NCT06931080 · Official ClinicalTrials.gov record · Otsuka Pharmaceutical Co., Ltd.
RecruitingPhase 2Berlin
Phase 2: testing DEX IR tablets for Attention-Deficit/Hyperactivity Disorder (ADHD)The indication of attention-deficit/hyperactivity disorder (ADHD) to be examined often occurs with other psychiatric disorders, and the majority of adults with ADHD have at least one psychiatric comorbidity in their lives. Depression is one of the most common comorbidities in patients with ADHD.
NCT06967857 · Official ClinicalTrials.gov record · Prof. Dr. Frank Behrens
RecruitingNot a traditional drug phaseBozeman, Montana
Not a traditional drug phase: Speech-Gesture combinations for Autism DisorderThis research study investigates how hand gestures can support language comprehension and communication skills of hearing speaking, non-speaking, and/or minimally verbal individuals with Autism Spectrum Disorders (ASD), who are especially disadvantaged by the lack of accessible services in their rural communities. Individuals with other cognitive profiles, including Developmental Language Disorder (DLD), ADHD, Dyslexia, and others are welcome too.
NCT07054866 · Official ClinicalTrials.gov record · Montana State University
RecruitingNot a traditional drug phaseSan Francisco, California
Not a traditional drug phase: Trigeminal Nerve Stimulation for Attention Deficit Disorder With Hyperactivity (ADHD)The goal of this clinical trial is to learn if external trigeminal nerve stimulation (eTNS) works to treat ADHD symptoms in children on the autism spectrum (ASD). It will also learn about the how well it works and tolerability of the eTNS device.
NCT07214545 · Official ClinicalTrials.gov record · University of California, San Francisco
RecruitingNot a traditional drug phaseOnna, Okinawa
Not a traditional drug phase: Behavioral Parent Training for ADHDThis study evaluates the feasibility and preliminary impacts of a new parent support program consisting of a series of educational videos, automatically delivered via a popular texting platform. The program content is focused on teaching parents strategies to better manage interactions with children in challenging situations many children experience, e.g., a transition to a non-preferred activity, waiting for delayed reward.
NCT07291453 · Official ClinicalTrials.gov record · Okinawa Institute of Science and Technology Graduate University
RecruitingNot a traditional drug phaseDallas, Texas
Not a traditional drug phase: Cedrus RB series response pad; Adtech Behnke-Fried micro-electrodes; Neuralynx or Blackrock electrophysiology system; Blackrock Cerestim or Natus Nicolet stimulator for Epilepsy IntractableThe purpose of the research is to better understand how the human brain accomplishes the basic cognitive tasks of learning new information, recalling stored information, making decisions or choices about presented information and self-control. These investigations are critical to better understand human cognition and to design treatments for disorders of learning, memory, decision making and cognitive control.
NCT07350551 · Official ClinicalTrials.gov record · University of Texas Southwestern Medical Center
RecruitingNot a traditional drug phasePoznan
Not a traditional drug phase: Moderate-Intensity Aerobic Exercise on Cycloergometer for ADHD - Attention Deficit Disorder With HyperactivityThis study aims to explore how six short, 15-minute self-regulation techniques affect the body and brain in a female adult with ADHD and stabilized bipolar disorder. The techniques being tested include: * Aerobic exercise * Controlled breathing (cyclic sighing) * Aromatherapy with lavender essential oil * Listening to specific music (Solfeggio 528 Hz) * Virtual reality relaxation with forest imagery * Emotional Freedom Technique (EFT) tapping One session of quiet sitting with eyes open serves as a comparison.
NCT07437833 · Official ClinicalTrials.gov record · Poznan University of Physical Education
RecruitingNot a traditional drug phaseBethesda, Maryland
Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention De…Background: Attention deficit hyperactivity disorder (ADHD) is common in children. It can cause problems with attention and the ability to control actions and impulses.
NCT07566468 · Official ClinicalTrials.gov record · National Institute of Mental Health (NIMH)
RecruitingNot a traditional drug phaseBethesda, Maryland
Not a traditional drug phase: Psychotherapy for IrritabilityBackground: Irritability is defined as proneness to anger that may impair a person's ability to function. It is a common reason for why some children need mental health care.
NCT07640802 · Official ClinicalTrials.gov record · National Institute of Mental Health (NIMH)
RecruitingPhase 4Ottawa, Ontario
Phase 4: testing Methylphenidate hydrochloride extended-release capsules for Attention Deficit Hyperactivity DisorderThis study is evaluating the safety and effectiveness of Foquest (multilayer-release methylphenidate), a once-daily extended-release medication for attention-deficit/hyperactivity disorder (ADHD), in adults aged 65 years and older. ADHD can persist into older age and is associated with reduced quality of life and difficulties with executive function.
NCT07710014 · Official ClinicalTrials.gov record · Dar Clinical Research Inc.
RecruitingPhase 3Dothan, Alabama
Phase 3: testing Solriamfetol Dose A for ADHDThis study is a Phase 3, multi-center, randomly assigned, 6-week, neither you nor the study doctors know who gets the real treatment, compared with a dummy treatment, parallel-group trial to assess the how well it works and safety of solriamfetol in children aged 6 to \<12 years with ADHD.
NCT07717879 · Official ClinicalTrials.gov record · Axsome Therapeutics, Inc.
RecruitingPhase 3Dothan, Alabama
Phase 3: testing Solriamfetol Dose A for ADHDThis study is a Phase 3, multi-center, randomly assigned, 6-week, neither you nor the study doctors know who gets the real treatment, compared with a dummy treatment, parallel-group trial to assess the how well it works and safety of solriamfetol in adolescents aged 12 to \<18 years with ADHD.
NCT07717892 · Official ClinicalTrials.gov record · Axsome Therapeutics, Inc.
RecruitingPhase 2Little Rock, Arkansas
Phase 2: testing ALKS 7290 for Attention Deficit Disorder With Hyperactivity (ADHD)This study wants to measure safety and the improvement in symptoms in subjects with ADHD when taking ALKS 7290 tablets compared with dummy treatment (placebo) tablets.
NCT07755410 · Official ClinicalTrials.gov record · Alkermes, Inc.
RecruitingPhase 3Gainesville, Florida
Phase 3: testing Centanafadine XR for Attention-deficit/Hyperactivity DisorderThe primary purpose of this study is to measure the how well it works of centanafadine once daily (QD) extended-release (XR) capsules in adults with attention-deficit/hyperactivity disorder (ADHD) and emotional dysregulation (ED).
NCT07759154 · Official ClinicalTrials.gov record · Otsuka Pharmaceutical Development & Commercialization, Inc.
RecruitingNot a traditional drug phaseTaipei, Taiwan
Not a traditional drug phase: testing methylphenidate for ADHDTo build a multimodal model combining neuropsychological, neurophysiological, and metabolomic measures to identify biomarkers predicting MPH-induced adverse effects and their underlying mechanisms, supporting individualized risk assessment in clinical practice.
NCT07900451 · Official ClinicalTrials.gov record · National Taiwan University Hospital
RecruitingNot a traditional drug phaseHsinchu
Not a traditional drug phase: Generative artificial intelligence assisted diary platform home-based intervention for ADHD - Attention Deficit Disorder With HyperactivityThe goal of this clinical trial is to measure the effectiveness of online diary platforms for socio-emotional learning training in children with attention deficit hyperactivity disorder (ADHD). The main questions it aims to answer are: Does the online diary platform training enhance children's emotion regulation and its connection to positive thinking?
NCT07922018 · Official ClinicalTrials.gov record · National Taiwan University Hospital
RecruitingNot a traditional drug phaseKuala Lumpur, Kuala Lumpur
Not a traditional drug phase: Broad-spectrum multivitamin and mineral supplementation for Attention Deficit Hyperactivity Disorder (ADHD)Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition in children that can affect attention, behavior, learning, and daily functioning. Nutritional status, gut health, and sleep and circadian patterns may influence ADHD-related symptoms.
NCT07922252 · Official ClinicalTrials.gov record · UCSI University