RecruitingPhase 3Tuscaloosa, Alabama
Phase 3: testing Tirzepatide for Metabolic Dysfunction-Associated Steatotic Liver DiseaseThe main purpose of the SYNERGY-OUTCOMES study is to find out whether retatrutide and tirzepatide can prevent major adverse liver outcomes (MALO) in people with high-risk metabolic dysfunction-associated steatotic liver disease (MASLD). The study will enroll adults who have MASLD based on non-invasive tests (NITs), which indicate they are more likely to develop MALO.
NCT07165028 · Official ClinicalTrials.gov record · Eli Lilly and Company
RecruitingPhase 2Shenzhen, Guangdong
Phase 2: testing Retatrutide (LY3437943) for ObesityPhase 2, multicenter, randomly assigned, neither you nor the study doctors know who gets the real treatment, compared with a dummy treatment study evaluating once-weekly subcutaneous retatrutide (LY3437943) at multiple maintenance dose levels versus dummy treatment (placebo) in adults with obesity or overweight with weight-related comorbidities (without type 2 diabetes), alongside standardized diet and physical activity counseling.
NCT07467447 · Official ClinicalTrials.gov record · Hudson Biotech