Not medical advice. This website is not medical advice, a diagnosis, a match to a trial, or a recommendation to join a study. Listings are plain-English rewrites of public ClinicalTrials.gov records. Whether a site is still enrolling, and whether you qualify, can only be confirmed by the study team and your clinician. Source registry: ClinicalTrials.gov. Editorial rules: methodology.
RecruitingNot a traditional drug phaseobservationalRules rewrite
Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System
Inflammatory or degenerative diseases of the brain and spinal cord, such as multiple sclerosis, may be related to problems with an individual s immune system. However, more information is needed on the ways in which the cells of the immune system interact with the central nervous system (CNS).
This is an observational study. You are not assigned a new experimental drug. Researchers measure what already happens in your care or in daily life.
Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
What the registry says happens
This listing is observational (StudyType). The registry does not assign a new experimental drug as the study intervention.
They plan to enroll about 2,400 people at Bethesda. Taking part typically means study visits and measurements plus check-ins.
Official title (unrewritten)
Comprehensive Multimodal Analysis of Patients With Neuroimmunological Diseases of the CNS
Primary outcome (registry wording): Disease progression as assessed by clinical and MRI criteria.
Who it is for (from inclusion criteria)
Ages 1 Month to 99 Years
PATIENT (FOR IN-PERSON AND TELEMEDICINE SUB-COHORTS):
Presentation with a clinical syndrome consistent with immune-mediated CNS disorder and/or
Neuroimaging evidence of inflammatory and/or demyelinating/dysmyelinating CNS disease
At least 12 years old at the time of enrollment
Willing to share medical records (including past MRI results) with the study team
For in-person sub-cohort: Able to undergo the required procedures, including LP, MRI and clinical/functional evaluations
Who the registry excludes
(FOR IN-PERSON AND TELEMEDICINE SUB-COHORTS):
Significant medical condition that would make participation in research part of evaluation impossible or risky
For in-person sub-cohort: Medical contraindications for MRI (i.e. any non-organic implant or other device such as a cardiac pacemaker or infusion pump or other metallic implants, objects or body piercings that cannot be removed)
Unwilling to consent for collection of biological samples or their cryopreservation
PATIENT who can join FOR PROCESSING OF COLLECTED BIOLOGICAL SAMPLES:
Presentation with a clinical syndrome consistent with immune-mediated CNS disorder and/or
Neuroimaging evidence of inflammatory and/or demyelinating/ dysmyelinating CNS disease
We will investigate the clinical manifestations and molecular genetic defects of heritable urologic malignant disorders. Families with urologic malignancy with known or suspected genetic basis will be enrolled.
This protocol will evaluate patients with systemic lupus erythematosus (SLE) and their relatives to learn more about how the disease develops and changes over time. It will also study genetic factors that make a person susceptible to SLE.
This study is designed to explore the genetics and pathophysiology of diseases presenting with intermittent fever, including familial Mediterranean fever, TRAPS, hyper-IgD syndrome, and related diseases. The following individuals may be eligible for this natural history study: 1) patients with known or suspected familial Mediterranean fever, TRAPS, hyper-IgD syndrome or related disorders; 2) relatives of these patients; 3) healthy, normal volunteers 7 years of age or older.
The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.
What phase is NCT00794352?
Not a traditional drug phase. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
Can PlainTrials tell me if I qualify for NCT00794352?
No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.