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RecruitingPhase 2interventionalRules rewrite

Phase 2: testing NMDAE plus AO for Schizophrenia

Previous studies found that some NMDA-enhancing agents were able to improve clinical symptoms of patients with schizophrenia. In addition, several drugs with antioxidant properties have been tested in clinical trials for the treatment of schizophrenia too.

Official registry: https://clinicaltrials.gov/study/NCT04959201 · China Medical University Hospital · enrollment listed as 90

What this phase means

Phase 2: researchers already know a roughly safe dose (from phase 1). This stage asks whether the treatment actually helps the condition, and watches side effects more closely.

Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

What the registry says happens

If you join, the listed intervention(s) are NMDAE plus AO, or NMDAE plus Placebo Cap. The registry lists allocation as randomized. Previous studies found that some NMDA-enhancing agents were able to improve clinical symptoms of patients with schizophrenia.

They plan to enroll about 90 people at Taichung. Taking part typically means taking a study drug (or dummy pill) plus check-ins.

Official title (unrewritten)

Combination of NMDA-enhancing and Antioxidant Treatments for Schizophrenia

Interventions: NMDAE plus AO, NMDAE plus Placebo Cap

Primary outcome (registry wording): Change of Positive and Negative Syndrome Scale (PANSS)

Who it is for (from inclusion criteria)

  • Ages 18 Years to 65 Years
  • Have a DSM-5 (American Psychiatric Association) diagnosis of schizophrenia
  • Remain symptomatic but without clinically significant fluctuation, while their antipsychotic doses are unchanged for at least 3 months and will be maintained during the period of the 12-week trial
  • PANSS total score ≥ 60

Public study contact (from the registry)

Hsien-Yuan Lane, M.D., Ph.D

886 4 22052121

hylane@gmail.com

Published on ClinicalTrials.gov. Contact them as a possible participant. They decide eligibility.

Sites listed on ClinicalTrials.gov

1 listed

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FAQ about this NCT record

Is NCT04959201 still recruiting?

The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.

What phase is NCT04959201?

Phase 2. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

Can PlainTrials tell me if I qualify for NCT04959201?

No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.

How to read a ClinicalTrials.gov record · Questions to ask the coordinator · Glossary