Not medical advice. This website is not medical advice, a diagnosis, a match to a trial, or a recommendation to join a study. Listings are plain-English rewrites of public ClinicalTrials.gov records. Whether a site is still enrolling, and whether you qualify, can only be confirmed by the study team and your clinician. Source registry: ClinicalTrials.gov. Editorial rules: methodology.
RecruitingNot a traditional drug phaseinterventionalRules rewrite
Not a traditional drug phase: Exercise for Cirrhosis With Hepatocellular Carcinoma
The main purpose of the study is to characterize the production of hepatokines (FGF21 and Follistatin) in response to a submaximal exercise on an ergocycle, in patients with hepatocellular carcinoma. The effect of exercise on hepatokines and metabolites production in liver cancer patients is not known.
This study does not use the classic phase 1–4 drug ladder. It may be a device, a behavior program, a surgery timing study, or an early feasibility test.
Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
What the registry says happens
If you join, the listed intervention(s) are Exercise. The registry lists allocation as na. The main purpose of the study is to characterize the production of hepatokines (FGF21 and Follistatin) in response to a submaximal exercise on an ergocycle, in patients with hepatocellular carcinoma.
They plan to enroll about 12 people at 2 sites. Taking part typically means study visits and measurements plus check-ins.
Official title (unrewritten)
Effect of Acute Endurance Exercise on the Production of FGF21 and Follistatin in Patients With Hepatocellular Carcinoma
Interventions: Exercise
Primary outcome (registry wording): Systemic hepatokines rates (FGF-21 and follistatin)
Who it is for (from inclusion criteria)
Ages 18 Years to 80 Years
Hepatocellular carcinoma developed on cirrhosis
Cirrhosis of any etiology, defined by a liver elasticity measurement \>15kPa or a history of cirrhosis decompensation
Hepatocellular carcinoma with indication for treatment by immunotherapy or chemoembolization
Child-Pugh scores A and B7
Affiliation to french national social security system
Who the registry excludes
Hepatic encephalopathy grade II or higher
Surgery performed within 30 days prior to inclusion visit
Muscle injury within 3 months of inclusion
Pregnant or breast-feeding women
Patients under legal protection (guardianship, curatorship, safeguard of justice)
Participation in another clinical trial within 10 days of inclusion
This study will collect blood from patients with cancer to study the level of cells which decrease the immune response (suppressor cells) before and after chemotherapy. Patients 18 years of age and older with cancer may participate.
This study aims to provide long-term follow-up care of patients previously enrolled in a vaccine study that involved poxviral vectors. Vectors are sequences of genetic material that can be used to introduce specific genes into genetic makeup.
Background: \- Noncirrhotic Portal Hypertension (NCPH) is caused by liver diseases that increase pressure in the blood vessels of the liver. It seems to start slowly and not have many warning signs.
The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.
What phase is NCT07189624?
Not a traditional drug phase. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
Can PlainTrials tell me if I qualify for NCT07189624?
No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.