Not medical advice. This website is not medical advice, a diagnosis, a match to a trial, or a recommendation to join a study. Listings are plain-English rewrites of public ClinicalTrials.gov records. Whether a site is still enrolling, and whether you qualify, can only be confirmed by the study team and your clinician. Source registry: ClinicalTrials.gov. Editorial rules: methodology.
RecruitingPhase 1 / Phase 2interventionalRules rewrite

Phase 1 / Phase 2: testing Pumitamig for Hepatocellular Carcinoma (HCC)

This study wants to measure the whether it is safe and how hard side effects are to live with of Pumitamig alone or in combination with Ipilimumab in participants with first-line advanced or unresectable Hepatocellular Carcinoma (HCC)

Official registry: https://clinicaltrials.gov/study/NCT07291076 · Bristol-Myers Squibb · enrollment listed as 198

What this phase means

Phase 2: researchers already know a roughly safe dose (from phase 1). This stage asks whether the treatment actually helps the condition, and watches side effects more closely.

Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

What the registry says happens

If you join, the listed intervention(s) are Pumitamig, or Ipilimumab. The registry lists allocation as randomized. This study wants to measure the whether it is safe and how hard side effects are to live with of Pumitamig alone or in combination with Ipilimumab in participants with first-line advanced or unresectable Hepatocellular Carcinoma (HCC)

They plan to enroll about 198 people at 67 sites. Taking part typically means taking a study drug (or dummy pill) plus check-ins.

Official title (unrewritten)

ROSETTA HCC-206: An Open-Label, Multi-Center, Randomized Phase 1/2 Study of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC)

Interventions: Pumitamig, Ipilimumab

Primary outcome (registry wording): Number of participants with adverse events (AEs)

Who it is for (from inclusion criteria)

  • Ages 18 Years to any
  • Participants must have a histologically confirmed diagnosis of locally advanced or unresectable Hepatocellular Carcinoma (HCC)
  • Participants must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
  • Participants must have no prior systemic therapy for advanced/ unresectable HCC
  • Participants must have measurable disease as per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1

Public study contact (from the registry)

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com

855-907-3286

Clinical.Trials@bms.com

Published on ClinicalTrials.gov. Contact them as a possible participant. They decide eligibility.

Sites listed on ClinicalTrials.gov

67 listed

+ 56 sites outside the US on the same record

Related recruiting trials in this snapshot

FAQ about this NCT record

Is NCT07291076 still recruiting?

The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.

What phase is NCT07291076?

Phase 1 / Phase 2. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

Can PlainTrials tell me if I qualify for NCT07291076?

No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.

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