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RecruitingNot a traditional drug phaseobservationalRules rewrite
A Study of Guselkumab Treatment Persistence in Psoriatic Arthritis Participants
This watch-and-measure (no experimental treatment required) study aims to assess the 1-year persistence of guselkumab in adult patients with psoriatic arthritis (an inflammatory disease that affects the joints in participants with psoriasis, a skin condition that causes red, scaly patches).
This is an observational study. You are not assigned a new experimental drug. Researchers measure what already happens in your care or in daily life.
Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
What the registry says happens
This listing is observational (StudyType). The registry does not assign a new experimental drug as the study intervention.
They plan to enroll about 200 people at Lille. Taking part typically means study visits and measurements plus check-ins.
Official title (unrewritten)
A Real-World, Prospective Study of Guselkumab Treatment Persistence in Psoriatic Arthritis Patients
Primary outcome (registry wording): Proportion of Participants Still Receiving Treatment at 1 Year
Who it is for (from inclusion criteria)
Ages 18 Years to any
Have a confirmed diagnosis of psoriatic arthritis (PsA) as determined by a rheumatologist with reference to ClASsification criteria for Psoriatic ARthritis (CASPAR)
Start guselkumab as a first, second, third, or fourth line of disease-modifying antirheumatic drug (bDMARD) therapy for the indication of PsA as part of standard clinical practice at the time of enrollment into the watch-and-measure (no experimental treatment required) study
Initiating guselkumab treatment according to Summary of Product Characteristics (SmPC) indication
The treatment decision must be taken by the participating rheumatologist prior to, and independently of the patient's inclusion into the study, following clinical practice in accordance with local and overarching guidelines and local regulations
Must have received the information note, given his/her oral agreement and has not objected to the collection of his/her data in accordance with French requirements
Who the registry excludes
Have already taken a specific interleukin-23 inhibitor (IL-23i) treatment
Are receiving combination therapy: 2 or more targeted therapies (biotherapy, Janus kinase \[JAK\] inhibitor, phosphodiesterase 4 (PDE4) inhibitor) indicated for PsA/PsO at the same time
Has a contra-indication to guselkumab according to the SmPC (for hypersensitivity or due to active clinically important infection, example active tuberculosis)
Unwilling or unable to participate in long-term data collection
Currently enrolled in any treatment study or any Janssen-Cilag France-sponsored watch-and-measure (no experimental treatment required) clinical study
Is under guardianship or curatorship, judicial protection, future protection mandate or under family authorization
Treatment of moderate to severe Psoriasis (Pso) and Psoriasis-Arthritis (PsA) is largely confined to systemic therapy in Germany. Systemic therapy includes conventional systemic therapy (e.g.
Glucocorticoids remain to be among the most important and most frequently used anti-inflammatory and immunosuppressive or immune-modulatory acting drugs to treat rheumatic (and other) diseases. Unfortunately, glucocorticoids also exert undesired effects, especially if higher dosages have to be given over longer periods of time.
The purpose of this pediatric study is to measure the drug levels, how well it works and safety of Deucravacitinib in children and adolescent participants aged 4 to \<18 years with moderate to severe plaque psoriasis. This study includes two cohorts; Cohort 1 (age 12 to \<18 years) and Cohort 2 (age 4 to \<12 years), with two parts; for each cohort.
The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.
What phase is NCT07532226?
Not a traditional drug phase. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
Can PlainTrials tell me if I qualify for NCT07532226?
No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.