Not medical advice. This website is not medical advice, a diagnosis, a match to a trial, or a recommendation to join a study. Listings are plain-English rewrites of public ClinicalTrials.gov records. Whether a site is still enrolling, and whether you qualify, can only be confirmed by the study team and your clinician. Source registry: ClinicalTrials.gov. Editorial rules: methodology.
RecruitingNot a traditional drug phaseobservationalRules rewrite
Not a traditional drug phase: MRI Visit for PCOS
This study wants to determine how polycystic ovary syndrome (PCOS) impacts overall brain health, such as cerebral blood flow (CBF), brain structure and connectivity, and cognitive performance. 45 reproductive aged (18-45 years) individuals with ovaries, with and without PCOS, will be enrolled to complete brain structure and CBF scans via magnetic resonance imaging (MRI) over 2 testing visits and can expect to be on study for approximately 5 hours over a 1 to 3 month period.
This is an observational study. You are not assigned a new experimental drug. Researchers measure what already happens in your care or in daily life.
Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
What the registry says happens
This listing is observational (StudyType). The registry does not assign a new experimental drug as the study intervention.
They plan to enroll about 45 people at Madison. Taking part typically means using or being fitted with a device plus check-ins.
Official title (unrewritten)
Functional and Structural Impacts of Polycystic Ovary Syndrome (PCOS) on Brain Health
Interventions: MRI Visit, Laboratory Visit
Primary outcome (registry wording): Cerebral Blood Flow (CBF) at rest
Who it is for (from inclusion criteria)
Ages 18 Years to 45 Years
Women only
(Participants with PCOS):
Rotterdam criteria demonstrating two out of the three criteria. These are:
Presence of clinical hyperandrogenism or biochemical hyperandrogenism
A history of irregular menstrual cycles
Presence of polycystic ovarian morphology on ultrasound
who can join (Healthy Controls):
Regular menstrual cycles (not meeting criteria for irregular cycles above)
Who the registry excludes
Preexisting diagnosis of type 1 diabetes
Severe obesity (body mass index (body-mass index (BMI)) greater than 45kg/m2)
Preexisting diagnosis of hypertension requiring antihypertensive medication or blood pressure of greater than 160/100 on two separate occasions during clinical care
History of neurologic disease or stroke
History of myocardial infarction or deep venous thrombosis
Endometriosis confirmed by prior laparoscopy
Autoimmune conditions including lupus, multiple sclerosis, and active malignancy
We will investigate the clinical manifestations and molecular genetic defects of heritable urologic malignant disorders. Families with urologic malignancy with known or suspected genetic basis will be enrolled.
This protocol will evaluate patients with systemic lupus erythematosus (SLE) and their relatives to learn more about how the disease develops and changes over time. It will also study genetic factors that make a person susceptible to SLE.
This study is designed to explore the genetics and pathophysiology of diseases presenting with intermittent fever, including familial Mediterranean fever, TRAPS, hyper-IgD syndrome, and related diseases. The following individuals may be eligible for this natural history study: 1) patients with known or suspected familial Mediterranean fever, TRAPS, hyper-IgD syndrome or related disorders; 2) relatives of these patients; 3) healthy, normal volunteers 7 years of age or older.
The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.
What phase is NCT07727512?
Not a traditional drug phase. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
Can PlainTrials tell me if I qualify for NCT07727512?
No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.