Not medical advice. This website is not medical advice, a diagnosis, a match to a trial, or a recommendation to join a study. Listings are plain-English rewrites of public ClinicalTrials.gov records. Whether a site is still enrolling, and whether you qualify, can only be confirmed by the study team and your clinician. Source registry: ClinicalTrials.gov. Editorial rules: methodology.
PlainTrials
RecruitingNot a traditional drug phaseobservationalRules rewrite

Not a traditional drug phase: testing High-dose methotrexate-based therapy for Primary Central Nervous System Lymphoma (PCNSL)

This project aims to establish and prospectively register a longitudinal, multimodal biobank for primary central nervous system lymphoma (PCNSL). The study will primarily enroll patients undergoing needle biopsy or surgical resection of lesions involving the brain, spinal cord, or meninges, with a pathological diagnosis of central nervous system lymphoma.

Official registry: https://clinicaltrials.gov/study/NCT07842835 · Xiaohui Ren · enrollment listed as 400

What this phase means

This is an observational study. You are not assigned a new experimental drug. Researchers measure what already happens in your care or in daily life.

Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

What the registry says happens

This listing is observational (StudyType). The registry does not assign a new experimental drug as the study intervention.

They plan to enroll about 400 people at 3 sites. Taking part typically means taking a study drug (or dummy pill) plus check-ins.

Official title (unrewritten)

Registry of an Integrated Longitudinal Multimodal Biospecimen Biobank for Primary Central Nervous System Lymphoma in China（CLIMB）

Interventions: High-dose methotrexate-based therapy, Bruton tyrosine kinase inhibitor-based therapy

Primary outcome (registry wording): Baseline data completeness rate

Who it is for (from inclusion criteria)

  • Ages 18 Years to 100 Years
  • General Criteria for Patient Participants
  • Radiological findings suspicious for primary central nervous system lymphoma (PCNSL)
  • Scheduled to undergo needle biopsy or surgical resection of a lesion involving the brain, spinal cord, or meninges
  • Patient participants must additionally meet all of the following criteria:
  • Histopathologically confirmed PCNSL
  • Able to undergo magnetic resonance imaging examinations
  • Non-PCNSL Disease Control Cohort

Public study contact (from the registry)

Xiaohui Ren, MD

+86-010-59975567

xiaohuiren@mail.ccmu.edu.cn/xiaohuiren@aliyun.com

Published on ClinicalTrials.gov. Contact them as a possible participant. They decide eligibility.

Sites listed on ClinicalTrials.gov

3 listed

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FAQ about this NCT record

Is NCT07842835 still recruiting?

The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.

What phase is NCT07842835?

Not a traditional drug phase. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

Can PlainTrials tell me if I qualify for NCT07842835?

No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.

How to read a ClinicalTrials.gov record · Questions to ask the coordinator · Glossary