This single-center randomly assigned comparative study is designed to compare the effectiveness of tirzepatide and transcutaneous low-frequency auricular vagus nerve stimulation in adults with class I obesity and without chronic non-communicable diseases. The study focuses on changes in body weight, anthropometric indices, epicardial and visceral adipose tissue, body composition, behavioral factors, skeletal muscle characteristics, and cardiac structure and function.
Official registry: https://clinicaltrials.gov/study/NCT07866183 · National Medical Research Center for Therapy and Preventive Medicine · enrollment listed as 120
This study does not use the classic phase 1–4 drug ladder. It may be a device, a behavior program, a surgery timing study, or an early feasibility test.
Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
If you join, the listed intervention(s) are Tirzepatide, or Transcutaneous auricular vagus nerve stimulation. The registry lists allocation as randomized. This single-center randomly assigned comparative study is designed to compare the effectiveness of tirzepatide and transcutaneous low-frequency auricular vagus nerve stimulation in adults with class I obesity and without chronic non-communicable diseases.
They plan to enroll about 120 people at Moscow. Taking part typically means taking a study drug (or dummy pill), using or being fitted with a device plus check-ins.
Trial of Innovative Fat-loss Focused Approaches in Patients With Class I Obesity: a Comparative Study
Interventions: Tirzepatide, Transcutaneous auricular vagus nerve stimulation
Primary outcome (registry wording): Percentage reduction in body weight
Elizaveta Rogozhkina, MD, PhD
Published on ClinicalTrials.gov. Contact them as a possible participant. They decide eligibility.
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NCT00001373 · Official ClinicalTrials.gov record · National Human Genome Research Institute (NHGRI)
The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.
Not a traditional drug phase. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.
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